ISSN: 1305-9327

 
 

VOLUME: 6 NUMBER: 1
 
 
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9 - Recurrent spontaneous ovarian hyperstimulation syndrome with hypothyroidism: a case report
   
Ebru Akbay, Cihangir Uzunçakmak, Nadire Sevda İdil, Zeynep Akçiğ, Gül Özel, Levent Yaşar
   
  ABSTRACT
   
  Ovarian hyperstimulation most commonly occurs iatrogenically in association with assisted reproductice technologies. Incidence of iatrogenic ovarian hyperstimulation is 0,2-1%. There are only a few cases of pregnancies associated with recurrent spontaneous ovarian hyperstimulation. This report describes a case in which a naturally conceived pregnancy was associated with recurrent spontaneous ovarian hyperstimulation with hypothyroidism. The etiopathogenesis of spontaneous ovarian hyperstimulation is unclear. It was suggested that polycystic ovary syndrome, twin and molar pregnancies in which the endogenous hCG levels were higher than normal, mutation in the FSH receptor could be risk factors for spontaneous ovarian hyperstimulation. Hypothyroidism is another risk factor for the development of spontaneous ovarian hyperstimulation.
   
  Keywords
  Ovarian hyperstimulation syndrome, hypothyroidism
   
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